Aplicación de corriente transcraneal directa como terapia no invasiva en trastornos de la conducta alimentaria: una propuesta de intervención
Publicado Jun 22, 2020
Resumen
La estimulación transcraneal de corriente directa constituye una técnica prometedora para el tratamiento de trastornos psiquiátricos como puede ser la anorexia nerviosa. La forma de actuación es a través de la regulación de la actividad cerebral aplicada principalmente en la zona de la corteza prefrontal dorsolateral. En el presente trabajo se revisan los principios de la estimulación transcraneal de corriente directa a través de los electrodos y cómo influye la intensidad, la duración y el tipo de procedimientos de aplicación en los resultados; la patogenia de la anorexia nerviosa, las diferentes áreas que se encuentran alteradas en cuanto a su funcionamiento, asi como lo estudios llevados a cabo en la corteza prefrontal dorsolateral y los diferentes estudios experimentales de tratamiento en esta tipología de pacientes mediante esta técnica en los últimos años. Se expone también una posible propuesta de intervención basándonos en las evidencias encontradas en los diferentes trabajos revisados introduciendo algunas mejoras, con lo que se pretende dar a conocer con mayor profundidad la efectividad del tratamiento mediante tDCS en futuras investigaciones.
##plugins.themes.bootstrap3.article.details##
Cómo citar
Descargar Cita
Descargas
Citas
American Psychiatric Association (1994). Diagnostic and statistical manual of mental disorders (4a. ed).
Bär, K. J., Berger, S., Schwier, C., Wutzler, U., and Beissner, F. (2013). Insular dysfunction and descending pain inhibition in anorexia nervosa. Acta Psychiatr. Scand, 127, 269–278. doi: 10.1111/j.1600-0447.2012.01896.x
Berryhill, M. E., Peterson, D. J., Jones, K. T., & Stephens, J. A. (2014). Hits and misses: leveraging tDCS to advance cognitive research. Frontiers in psychology, 5, 800. doi: 10.3389/fpsyg.2014.00800
Bodell. (2010). Current treatment for anorexia nervosa: Efficacy, safety, and adherence. Psychology Research and Behavior Management, 91. doi: 10.2147/PRBM.S13814
Braun ,CM, Chouinard, M.J. (1992). Is anorexia nervosa a neuropsychological disease? Neuropsychology, 3, 171–212. doi: 10.1007/bf01108842
Brooks, S. J., O'Daly, OG., Uher, R., Friederich, H. C., Giampietro, V., Brammer, M., et al. (2011). Differential neural responses to food images in women with bulimia versus anorexia nervosa. PLoS ONE 6, 22259. doi: 10.1371/journal.pone.0022259
Brunoni, A. R., Amadera, J., Berbel, B., Volz, M. S., Rizzerio, B. G., and Fregni, F. (2011). A systematic review on reporting and assessment of adverse effects associated with transcranial direct current stimulation. Int. J. Neuropsychopharmacol. 14, 1133–1145. doi: 10.1017/S1461145710001690
Casper, R. C. (2006). The “drive for activity” and “restlessness” in anorexia nervosa: potential pathways. J. Affect. Disord. 92, 99–107. doi: 10.1016/j.jad.2005.12.039
Costanzo, F., Menghini, D., Maritato, A., Castiglioni, M. C., Mereu, A., Varuzza, C., Zanna, V., & Vicari, S. (2018). New Treatment Perspectives in Adolescents With Anorexia Nervosa: The Efficacy of Non-invasive Brain-Directed Treatment. Frontiers in Behavioral Neuroscience, 12, 133. doi: 10.3389/fnbeh.2018.00133
Dalton, B., Bartholdy, S., Campbell, I. C., & Schmidt, U. (2018). Neurostimulation in Clinical and Sub-clinical Eating Disorders: A Systematic Update of the Literature. Current Neuropharmacology, 16(8), 1174-1192. doi: 10.2174/1570159X16666180108111532
Ehrlich, S., Geisler, D., Ritschel, F., King, J., Seidel, M., Boehm, I., Breier, M., Clas, S., Weiss, J., Marxen, M., Smolka, M., Roessner, V., & Kroemer, N. (2015). Elevated cognitive control over reward processing in recovered female patients with anorexia nervosa. Journal of Psychiatry & Neuroscience, 40(5), 307-315. doi:10.1503/jpn.140249
Ellison, Z., Foong, J., Howard, R., Bullmore, E., Williams, S., & Treasure, J. (1998). Functional anatomy of calorie fear in anorexia nervosa. The Lancet, 352(9135), 1192. doi: 10.1016/S0140-6736(05)60529-6
Esmaeilpour, Z., Shereen, A. D., Ghobadi‐Azbari, P., Datta, A., Woods, A. J., Ironside, M., & Ekhtiari, H. (2019). Methodology for tDCS integration with fMRI. Human Brain Mapping. doi: 10.1002/hbm.24908
Fladung, A. K., Grön, G., Grammer, K., Herrnberger, B., Schilly, E., Grasteit, S., ... & von Wietersheim, J. (2010). A neural signature of anorexia nervosa in the ventral striatal reward system. American Journal of Psychiatry, 167(2), 206-212. doi: 10.1176/appi.ajp.2009.09010071
Fonteneau, C., Redoute, J., Haesebaert, F., Le Bars, D., Costes, N., Suaud-Chagny, M. F., et al. (2018). Frontal transcranial direct current stimulation induces dopamine release in the ventral striatum in human. Cereb. Cortex 28, 2636–2646. doi: 10.1093/cercor/bhy093
Galusca, B., Costes, N., Zito, N. G., Peyron, R., Bossu, C., Lang, F., & Estour, B. (2008). Organic background of restrictive-type anorexia nervosa suggested by increased serotonin1A receptor binding in right frontotemporal cortex of both lean and recovered patients:[18F] MPPF PET scan study. Biological psychiatry, 64(11), 1009-1013. doi: 10.1016/j.biopsych.2008.06.006.
Gordon, G., Brockmeyer, T., Schmidt, U., & Campbell, I. C. (2019). Combining cognitive bias modification training (CBM) and transcranial direct current stimulation (tDCS) to treat binge eating disorder: Study protocol of a randomised controlled feasibility trial. BMJ Open, 9(10), e030023. doi:10.1136/bmjopen-2019-030023
Grunwald, M., Weiss, T., Assmann, B., and Ettrich, C. (2004). Stable asymmetric interhemispheric theta power in patients with anorexia nervosa during haptic perception even after weight gain: a longitudinal study. J. Clin. Exp. Neuropsychol. 26, 608–620. doi: 10.1080/13803390409609785
Hestad, K., Weider, S., Nilsen, K. B., Indredavik, M. S., & Sand, T. (2016). Increased frontal electroencephalogram theta amplitude in patients with anorexia nervosa compared to healthy controls. Neuropsychiatric Disease and Treatment, Volume 12, 2419-2423. doi:10.2147/NDT.S113586
Jáuregui-Lobera, I., & Martínez-Quiñones, J. V. (2018). Neuromodulation in eating disorders and obesity: A promising way of treatment? Neuropsychiatric Disease and Treatment, Volume 14, 2817-2835. doi:10.2147/NDT.S180231
Kaye, W. H., & Bailer, U. F. (2011). Understanding the neural circuitry of appetitive regulation in eating disorders. Biological psychiatry, 70(8), 704. doi: 10.1016/j.biopsych.2011.08.018
Kaye, W. H., Fudge, J. L., & Paulus, M. (2009). New insights into symptoms and neurocircuit function of anorexia nervosa. Nature Reviews Neuroscience, 10(8), 573. doi: 10.1038/nrn2682.
Kaye, W. H., Wierenga, C. E., Bailer, U. F., Simmons, A. N., Wagner, A., & Bischoff-Grethe, A. (2013). Does a shared neurobiology for foods and drugs of abuse contribute to extremes of food ingestion in anorexia and bulimia nervosa?. Biological psychiatry, 73(9), 836-842. doi: 10.1016/j.biopsych.2013.01.002
Khedr, E. M., Elfetoh, N. A., Ali, A. M., & Noamany, M. (2014). Anodal transcranial direct current stimulation over the dorsolateral prefrontal cortex improves anorexia nervosa: A pilot study. Restorative neurology and neuroscience, 32(6), 789-797. doi: 10.3233/RNN-140392
Kekic, M., McClelland, J., Bartholdy, S., Boysen, E., Musiat, P., Dalton, B., Tiza, M., David, A. S., Campbell, I. C., & Schmidt, U. (2017). Single-Session Transcranial Direct Current Stimulation Temporarily Improves Symptoms, Mood, and Self-Regulatory Control in Bulimia Nervosa: A Randomised Controlled Trial. PLOS ONE, 12(1), e0167606. doi:10.1371/journal.pone.0167606
Laghi, F., Pompili, S., Zanna, V., Castiglioni, M. C., Criscuolo, M., Chianello, I., Mazzoni, S., & Baiocco, R. (2017). How adolescents with anorexia nervosa and their parents perceive family functioning? Journal of Health Psychology, 22(2), 197-207. doi: 10.1177/1359105315597055
Lee, D. J., Elias, G. J. B., & Lozano, A. M. (2018). Neuromodulation for the treatment of eating disorders and obesity. Therapeutic Advances in Psychopharmacology, 8(2), 73-92. doi: 10.1177/2045125317743435
Li, L. M., Uehara, K., & Hanakawa, T. (2015). The contribution of interindividual factors to variability of response in transcranial direct current stimulation studies. Frontiers in cellular neuroscience, 9, 181. doi: 10.3389/fncel.2015.00181
Lowe, C. J., Vincent, C., & Hall, P. A. (2017). Effects of Noninvasive Brain Stimulation on Food Cravings and Consumption: A Meta-Analytic Review. Psychosomatic Medicine, 79(1), 2-13. doi: 10.1097/PSY.0000000000000368
Macedo, I. C., de Oliveira, C., Vercelino, R., Souza, A., Laste, G., Medeiros, L. F., Scarabelot, V. L., Nunes, E. A., Kuo, J., Fregni, F., Caumo, W., & Torres, I. L. S. (2016). Repeated transcranial direct current stimulation reduces food craving in Wistar rats. Appetite, 103, 29-37. doi: 10.1016/j.appet.2016.03.014
McClelland, J., Bozhilova, N., Campbell, I., & Schmidt, U. (2013). A Systematic Review of the Effects of Neuromodulation on Eating and Body Weight: Evidence from Human and Animal Studies: The Effects of Neuromodulation on Eating and Body Weight. European Eating Disorders Review, 21(6), 436-455. doi: 10.1002/erv.2256
McClelland, J., Kekic, M., Bozhilova, N., Nestler, S., Dew, T., Van den Eynde, F., Schmidt, U. (2016). A randomised controlled trial of neuronavigated repetitive transcranial magnetic stimulation (rTMS) in anorexia nervosa. PLoS One, 11(3). doi: 10.1371/journal.pone.0148606
Michaud, A., Vainik, U., Garcia-Garcia, I., & Dagher, A. (2017). Overlapping Neural Endophenotypes in Addiction and Obesity. Frontiers in Endocrinology, 8, 127. https://doi.org/10.3389/fendo.2017.00127
Moffa, A. H., Brunoni, A. R., Nikolin, S., & Loo, C. K. (2018). Transcranial Direct Current Stimulation in Psychiatric Disorders. Psychiatric Clinics of North America, 41(3), 447-463. doi: 10.1016/j.psc.2018.05.002
Monteleone, A. M., Castellini, G., Volpe, U., Ricca, V., Lelli, L., Monteleone, P., & Maj, M. (2018). Neuroendocrinology and brain imaging of reward in eating disorders: A possible key to the treatment of anorexia nervosa and bulimia nervosa. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 80, 132-142. doi: 10.1016/j.pnpbp.2017.02.020
Phillipou, A., Abel, L. A., Castle, D. J., Hughes, M. E., Gurvich, C., Nibbs, R. G., & Rossell, S. L. (2015). Self perception and facial emotion perception of others in anorexia nervosa. Frontiers in psychology, 6, 1181. doi: 10.3389/fpsyg.2015.01181
Phillipou, A., Gurvich, C., Castle, D. J., Abel, L. A., and Rossell, S. L. (2015). Comprehensive neurocognitive assessment of patients with anorexia nervosa. World J. Psychiatry 22, 404–411. doi: 10.5498/wjp.v5.i4.404
Phillipou, A., Kirkovski, M., Castle, D. J., Gurvich, C., Abel, L. A., Miles, S., & Rossell, S. L. (2019). High‐definition transcranial direct current stimulation in anorexia nervosa: A pilot study. International Journal of Eating Disorders, 52(11), 1274-1280. doi: 10.1002/eat.23146
Phillipou, A., Rossell, S. L., Gurvich, C., Castle, D. J., & Abel, L. A. (2016). The eyes have it: Eye movements and anorexia nervosa. Australian and New Zealand Journal of Psychiatry, 50(8), 806-807. doi:10.1177/0004867416656260
Phillipou, A., Rossell, S. L., Gurvich, C., Castle, D. J., Troje, N. F., & Abel, L. A. (2016). Body image in anorexia nervosa: Body size estimation utilising a biological motion task and eyetracking. European Eating Disorders Review, 24(2), 131-138. doi: 10.1002/erv.2423
Phillipou, A., Rossell, S. L., Gurvich, C., Hughes, M. E., Castle, D. J., Nibbs, R. G., & Abel, L. A. (2016). Saccadic eye movements in anorexia nervosa. PLoS One, 11(3). doi: 10.1371/journal.pone.0152338
Ray, M. K., Sylvester, M. D., Helton, A., Pittman, B. R., Wagstaff, L. E., McRae, T. R., Turan, B., Fontaine, K. R., Amthor, F. R., & Boggiano, M. M. (2019). The effect of expectation on transcranial direct current stimulation (tDCS) to suppress food craving and eating in individuals with overweight and obesity. Appetite, 136, 1-7. doi: 10.1016/j.appet.2018.12.044
Seeger, G., Braus, D. F., Ruf, M., Goldberger, U., & Schmidt, M. H. (2002). Body image distortion reveals amygdala activation in patients with anorexia nervosa–a functional magnetic resonance imaging study. Neuroscience Letters, 326(1), 25-28. doi: 10.1016/S0304-3940(02)00312-9.
Steinglass, J. E., Walsh, B. T., & Stern, Y. (2006). Set shifting deficit in anorexia nervosa. Journal of the International Neuropsychological Society, 12(3), 431-435. doi: 10.1017/S1355617706060528
Strumila, R., Thiebaut, S., Jaussent, I., Seneque, M., Attal, J., Courtet, P., & Guillaume, S. (2019). Safety and efficacy of transcranial direct current stimulation (tDCS) in the treatment of Anorexia Nervosa. The open-label STAR study. Brain Stimulation, 12(5), 1325-1327. doi: 10.1016/j.brs.2019.06.017
Surowka, A. D., Ziomber, A., Czyzycki, M., Migliori, A., Kasper, K., & Szczerbowska-Boruchowska, M. (2018). Molecular and elemental effects underlying the biochemical action of transcranial direct current stimulation (tDCS) in appetite control. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 195, 199-209. doi:10.1016/j.saa.2018.01.061
Symms, M., Jäger, H., Schmierer, K., & Yousry, T. (2006). A review of structural magnetic resonance neuroimaging. In Neuroscience For Neurologists (pp. 343– 375). UK: World Scientific. doi: 10.1136/jnnp.2003.032714
Taghva, A., Corrigan, J. D., & Rezai, A. R. (2012). Obesity and brain addiction circuitry: implications for deep brain stimulation. Neurosurgery, 71(2), 224-238. doi: 10.1227/NEU.0b013e31825972ab
Uher, R., Murphy, T., Brammer, M. J., Dalgleish, T., Phillips, M. L., Ng, V. W., ... & Treasure, J. (2004). Medial prefrontal cortex activity associated with symptom provocation in eating disorders. American Journal of Psychiatry, 161(7), 1238-1246. doi:10.1176/appi.ajp.161.7.1238.
Val-Laillet, D, Aarts, E, Weber, B. (2015). Neuroimaging and neuromodulation approaches to study eating behavior and prevent and treat eating disorders and obesity. Neuroimage; 8, 1–31. doi: 10.1016/j.nicl.2015.03.016.
Vierheilig, N., Mühlberger, A., Polak, T., & Herrmann, M. J. (2016). Transcranial direct current stimulation of the prefrontal cortex increases attention to visual target stimuli. Journal of Neural Transmission, 123(10), 1195-1203. doi: 10.1007/s00702-016-1542-5.
Volkow, N. D., Wang, G.-J., Tomasi, D., & Baler, R. D. (2013). Obesity and addiction: Neurobiological overlaps: Overlaps between drug and food addiction. Obesity Reviews, 14(1), 2-18. doi:10.1111/j.1467-789X.2012.01031.x
Wagner, A., Aizenstein, H., Venkatraman, V. K., Fudge, J., May, J. C., Mazurkewicz, L., ... & Carter, C. (2007). Altered reward processing in women recovered from anorexia nervosa. American Journal of Psychiatry, 164(12), 1842-1849. doi: 10.1176/appi.ajp.2007.07040575
Walsh, B. T. (2013). The enigmatic persistence of anorexia nervosa. Am. J. Psychiatry 170, 477–484. doi: 10.1176/appi.ajp.2012.12081074
Zhang, H. W., Li, D. Y., Zhao, J., Guan, Y. H., Sun, B. M., & Zuo, C. T. (2013). Metabolic imaging of deep brain stimulation in anorexia nervosa: a 18F-FDG PET/CT study. Clinical nuclear medicine, 38(12), 943-948. doi: 10.1097/RLU.0000000000000261.